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UNFORMATTED ATTACHMENT PREVIEW
Answer the following questions using the study from the NEJM provided. 1. Describe the extended Glasgow outcome scale (GOSE)?  2. The investigators used the GOSE tool as their key outcome measure in this study – list two limitations in their approach.  3. List the key selection criteria for this trial.  9. a) b) c) What is blinding in a study?  What level of blinding was used in this study?  What is a potential risk of the approach taken by the investigators?  10. List three issues around the consenting process this study.  11. List four potential ethical considerations in planning this study.  12. Give two benefits and two limitations of having a multicentre study.  13. a) What is bias?
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